A team of scientists at UCSF has engineered a completely synthetic molecule that straitjackets the critical SARS-CoV-2 machinery that allows the virus to infect our cells causing the current pandemic. This new technology will be a game-changer in halting the spread of COVID-19, as researchers around the world are working on finding a safe and effective vaccine. Details of the research report are in a new paper, now available on the preprint server bioRxiv.
The treatment called "AeroNabs" is an aerosolized formulation that will be in the form of a nasal spray or inhaler to be used once daily. Since it is a nasal spray or inhaler, it can be self-administered easily. AeroNabs could provide powerful protection against COVID-19 until a vaccine becomes available, or it can be used in conjunction with a vaccine. Clinical trials will be underway soon and the researchers hope to make it readily available to the public as an inexpensive preventative treatment for COVID-19.
AeroNabls will be an effective molecular form of PPE that could serve as a powerful and reliable line of defense against COVID-19 used together with physical PPE and social distancing and wearing masks to decrease transmission of the virus.
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